Hyperemesis Gravidarum HG.

Diagnosis of Pregnancy.

***) Signs and symptoms of pregnancy in the 1st trimester include all of the following, except:

A. Nausea

B. Quickening

C. Frequency of micturition

D. Soreness of breast

E. Hegar's sign

 

Answer: B* Quickening

 

***) Which of the following hormones is produced by trophoblast:

A. Luteinizing hormone

B. Follicle stimulating hormone

C. Prolactin

D. Human chorionic gonadotropin

E. Oxytocin

 

Answer: D* Human chorionic gonadotropin

 

***) Positive pregnancy test in the urine depends on the presence of:

A. Human chorionic gonadotropin

B. Progesterone

C. Estrogen

D. Calcium

E. Cortisol

 

Answer: A* Human chorionic gonadotropin

 

***) A suspicion of pregnancy at 3 wks GA may be confirmed by one of the following:

A. History of morning sickness and nausea

B. Vaginal examination

C. Abdominal examination

D. Immunological pregnancy test (hCG)

E. Breast examination

 

Answer: D* Immunological pregnancy test (hCG)

 

***) Which of the following hormones decreases after the first trimester of pregnancy:

A. Progesterone

B. Prolactin

C. Human Chorionic Gonadotropin (HCG)

D. Human Placental Lactogen (HPL)

E. Estrogen

 

Answer: C* Human Chorionic Gonadotropin (HCG)

 

2. Pregnancy & Physiological Changes.

***) All of the following statements are true, except:

A. The maximum weight increase in the uncomplicated pregnancy is 12.5 kg

B. The cardiac output has risen markedly by 40 percent during pregnancy

C. There is a slight increase of pulse rate about 15 percent

D. There is a decrease in red cell mass

E. Fibrinogen level increases during pregnancy

 

Answer: D* There is a decrease in red cell mass

 

***) Regarding cardiovascular system in normal pregnancy, the following are increased except:

A. Heart rate

B. Stroke volume

C. Plasma volume

D. Hematocrit

E. Red blood cells

 

Answer: D* Hematocrit

 

***) Blood volume is increased from the total volume during pregnancy at near term by about:

A. 10%

B. 20%

C. 25%

D. 45%

E. 100%

 

Answer: D*45%

 

***) Regarding supine hypotension one of the following is true:

A. Pressure of the gravid uterus on the aorta

B. Pressure of the gravid uterus on vena cava inferior

C. Pressure of the gravid uterus on vena cava superior

D. Constipation during pregnancy

E. Excessive heart burn

 

Answer: B* Pressure of the gravid uterus on vena cava inferior

 

***) In pregnancy concerning maternal blood the following are correct, except:

A. Plasma transcortin concentration increase

B. Free cortisol concentration increase

C. Thyroxin binding globulin concentration increase

D. Free thyroxin index increase

E. Release of TSH is not increased

 

Answer: D* Free thyroxin index increase

 

***) In the normal pregnancy all of the following increase, except:

A. Plasma volume

B. Hepatic blood flow

C. Platelet count

D. White cells count

E. Cardiac output

 

Answer: C* Platelet count

 

***) Pregnancy leads to one of the following:

A. Prolongation of stomach emptying time and increased acidity

B. Shortening of stomach emptying time and increased acidity

C. Shortening of stomach emptying time and decreased acidity

D. Prolongation of stomach emptying time and no affection of acidity

E. Prolongation of stomach emptying time and decrease acidity

 

Answer: E* Prolongation of stomach emptying time and decrease acidity

 

***) All of the following occur in alimentary tract during pregnancy, except:

A. The gums become swollen

B. Excessive salivation may occur

C. Heartburn (reflux esophagitis) is common

D. The stomach tends to empty more rapidly

E. Slow peristalsis of the bowel

 

Answer: D* The stomach tends to empty more rapidly

 

***) The cause of heartburn in pregnancy is:

A. Increased gastric motility

B. Increased vagal nerve activity

C. Gastro-esophageal reflux

D. Duodeno-gastric reflux

E. Increased gastric emptying

 

Answer: C* Gastro-esophageal reflux

 

***) Breast tissue of 2mm nodule is normal for which gestational age:

A. 28 weeks

B. 36 weeks

C. 40 weeks

D. 42 weeks

E. 44 weeks

 

Answer: A* 28 weeks

 

· Prenatal Care OB04-OB10.

 

Prenatal Visits.

***) All of the following are aims of antenatal care, except:

A. To monitor the well being of the fetus

B. To establish and maintain the physical health of the mother

C. The ideal time for first antenatal visit is before 14 weeks of pregnancy

D. Screening for fetal congenital abnormality

E. Screening for endometrial carcinoma

 

Answer: E* Screening for endometrial carcinoma

 

***) The embryonic life starts at:

A. The 3rd week after ovulation

B. The 5th week after ovulation

C. The 7th week after ovulation

D. The 9th week after ovulation

E. The 11th week after ovulation

 

Answer: C* The 7th week after ovulation

 

***) All of the following factors may reduce intrauterine death of the fetus, except:

A. Proper antenatal care

B. Localization of placenta in the first trimester

C. Antenatal fetal monitoring

D. Correct timing of delivery

E. Prevention of prematurity

 

Answer: B* Localization of placenta in the first trimester

 

***) In preventing anemia during pregnancy the ideal oral iron compound is:

A. 20 mg of iron

B. 100 mg of iron

C. 200 mg of iron

D. 400 mg of iron

E. 1000 mg of iron

 

Answer: A*20 mg of iron

 

***) All of the following are ideal routine blood tests carried out at first visit to an antenatal clinic, except:

A. Blood grouping and rhesus

B. Hemoglobin

C. Serological tests for syphilis

D. Rubella antibodies

E. Renal functional tests

 

Answer: E* Renal functional tests

 

***) All of the following are restriction on coitus during pregnancy, except:

A. Threatened abortion

B. History of premature labor

C. History of post partum hemorrhage

D. History of ante partum hemorrhage

E. When membranes are ruptured

 

Answer: C* History of post partum hemorrhage

 

***) Abdominal palpation in the latter half of pregnancy reveals all of the following, except:

A. The fundal height

B. The lie of the fetus

C. Cephalo-pelvic disproportion

D. The presentation of the fetal cephalic or breech

E. Whether the presenting part in engaged or not

 

Answer: C* Cephalo-pelvic disproportion (in the laber)

 

***) At 16 weeks of pregnancy, the uterine fundus is felt at:

A. Just above the pubic margin

B. At the level of umbilicus

C. Midway between umbilicus and pubic margin

D. 2 cm above the pubis

E. 2 cm above the umbilicus

 

Answer: C* Midway between umbilicus and pubic margin

 

***) At 14 weeks pregnancy a uterus may felt large for dates because of the following, except:

A. Wrong dates

B. Uterine fibroid

C. Full bladder

D. Polyhydramnios

E. Multiple pregnancy

 

Answer: C* Full bladder

 

***) A large for date uterus may be due to all of the following conditions, except:

A. Multiple pregnancy

B. Hydatidiform mole

C. Oligohydramnios

D. Uterine fibroid with pregnancy

E. Error in dates

 

Answer: C* Oligohydramnios

 

***) Causes of large for date pregnancies are the following, except:

A. Multiple pregnancy

B. Polyhydramnios

C. Hydatiform mole

D. Intrauterine fetal death

E. Diabetes with pregnancy

 

Answer: D* Intrauterine fetal death

 

***) The following factors may lead to wrong dates of delivery, except:

A. An irregular cycle

B. Regular cycles but in excess of 28 days (35-42 days)

C. Regular cycles of 28 days

D. Patient's poor memory

E. Breast feeding

 

Answer: C* Regular cycles of 28 days

 

***) To reduce the risk of recurrence of neural tube defects in a woman planning to get pregnancy, she should be advised to take:

A. Iron tablets 20 mg/day

B. Calcium tablets 1 gm/day

C. Vitamin E 200 mg/day

D. Vitamin B complex

E. Folic acid tablets 4 mg/day

 

Answer: E* Folic acid tablets 4 mg/day

 

***) Counseling of a pregnant woman during antenatal care should include advice and education on all of the following except one:

A. Smoking

B. Alcohol abuse

C. Drug abuse

D. Avoiding infection

E. Water consumption

 

Answer: E* Water consumption

 

***) The last menstrual period for a lady was June 30, the expected date of delivery is approximately:

A. March 23rd

B. April 7th

C. March 28th

D. April 23rd

E. March 7th

 

Answer: B* April 7th

 

Prenatal Screening.

***) The most sensitive prognostic test in Rh-disease of pregnancy is:

A. Antibody titer

B. Past history

C. Spectrophotometric examination of the amniotic fluid

D. Urinary bilirubin level

E. Fetal movements

 

Answer: C* Spectrophotometric examination of the amniotic fluid

 

***) Indication of anti-D administration to Rh-negative mothers married to Rh-positive husbands includes all the following except:

A. Following abortion

B. Following delivery of Rh-negative baby

C. At 28 weeks of gestation

D. Following ectopic pregnancy

E. Following amniocentesis

 

Answer: B* Following delivery of Rh-negative baby

 

***) All of the following are indications for anti-D-gamma-globulin administration, except:

A. Abortion caused by blighted ovum

B. Abortion secondary to cervical incompetence

C. After amniocentesis

D. After attacks of ante partum hemorrhage

E. To Rh-negative unsensitized mother giving birth to Rh-positive fetus

 

Answer: A* Abortion caused by blighted ovum

 

***) Regarding the prevention of Rh-isoimmunization, all the following are true except:

A. All Rh-negative women should marry Rh-negative husbands

B. Anti-D to be given at 28 weeks or 32 weeks for pregnant patient with Rh-positive husband

C. Anti-D to be given within 72 hours after delivery in a patient with Rh-positive fetus

D. Anti-D to be given in Rh-negative patients with abortion (blighted ovum)

E. Anti-D immunoglobulin causes severe neonatal jaundice

 

Answer: D* Anti-D to be given in Rh-negative patients with abortion (blighted ovum)

 

***) The most common cause of fetal death in uterus in Rh-isoimmunization is:

A. Jaundice

B. Heart failure

C. Respiratory distress syndrome

D. Congenital anomalies

E. Kernicterus

 

Answer: E* Kernicterus

 

Prenatal Diagnosis.

***) The following information may be obtained from aspiration of amniotic fluid in the 2nd and 3rd trimester of pregnancy, except:

A. Cytogenetics

B. Fetal maturity

C. Detection of neural tube defect by measurement of alpha fetoprotein

D. Polydactyly

E. Rhesus disease

 

Answer: D* Polydactyly

 

***) Amniotic fluid is used to check up all of the following, except:

A. Chromosome analysis

B. Neural tube defects

C. Lung maturity of the fetus

D. Fetal hemoglobin

E. Inborn metabolic disease

 

Answer: E* Inborn metabolic disease

 

***) Which one of the following karyotyping is not matching:

A. Normal male - 46 XY

B. Turner syndrome - 45 XO

C. Female Down syndrome - 47 XX, +21

D. Female Edwards syndrome - 47 XX, +13

E. Klinefelter syndrome - 47 XXY

 

Answer: D* Female Edwards syndrome - 47 XX, +13

 

· Medical Conditions in Pregnancy OB13-OB23.

 

Iron Deficiency Anemia.

***) The most common anemia during pregnancy is:

A. Iron deficiency anemia

B. Pernicious anemia

C. Sickle cell anemia

D. Thalassemia

E. Hemolytic anemia

 

Answer: A* Iron deficiency anemia

 

***) Regarding iron deficiency anemia in pregnancy, all the following are true except:

Is related to social class

Is very common in multiple pregnancy

Is prevented with adequate diet only

Can usually be treated with oral iron

Is more common in multi parous women

 

Answer: C*Is prevented with adequate diet only

 

***) Factors causing iron deficiency anemia in pregnancy are all of the following, except:

Sickle cell disease

Lack of iron supplements

Poor diet

Bleeding

Mal absorption

 

Answer: A* Sickle cell disease

 

***) All of the following are causes of iron deficiency anemia during pregnancy, except:

Inadequate iron in the diet

Excessive blood loss

Infrequent pregnancies

Abnormal demand as in multiple pregnancy

Mal absorption

 

Answer: C* Infrequent pregnancies

 

***) Effects of iron deficiency anemia in pregnancy include all of the following, except:

Increased plasma volume

Increased cardiac output

Decreased peripheral resistance

Oxygen dissociation curve shifted to the left

Heart failure may occur in severe cases

 

Answer: D* Oxygen dissociation curve shifted to the left

 

Folate Deficiency Anemia.

***) Folic acid deficiency during pregnancy may occur from the following, except:

Multiple pregnancies

Low HCl acid in the stomach

Grand multi-parous women

Poor diet

Anticonvulsant therapy in epileptic pregnant women

 

Answer: B* Low HCl acid in the stomach

 

***) In folic acid deficiency during pregnancy the earliest changes are:

Erythrocyte macrocytosis

Megaloblastic anemia

Low concentration of serum folate

Increased urinary formiminoglutamic acid (FIGLA)

Hypersegmentation of neutrophils

 

Answer: C* Low concentration of serum folate

 

***) Megaloblastic anemia in pregnancy is mainly due to:

Iron deficiency

Vitamin B12 deficiency

Folic acid deficiency

Vitamin B1 excess

Hypoxia

 

Answer: C* Folic acid deficiency

 

Diabetes Mellitus DM.

***) In a pregnant patient with diabetes mellitus, all the following are true except:

Glucosuria is unreliable sign of control

Insulin requirement usually increases

Blood sugar should be maintained at approximately 160 mg/dl

Persistent hyperglycemia is worse than occasional hypoglycemia

Glycosylated Hb gives indication of previous long-term blood sugar levels

 

Answer: C* Blood sugar should be maintained at approximately 160 mg/dl

 

***) In diabetes mellitus associated with pregnancy all of the following statements are true, except:

There is higher risk of congenital abnormality

There is higher risk of fetal death during the last weeks of pregnancy

Usually insulin requirement is increased

Delivery is always by caesarian section

Stabilization of diabetes should be done as early as possible during pregnancy

 

Answer: D* Delivery is always by caesarian section

 

***) All of the following are adverse effect of diabetes on pregnancy, except:

Increased risk of microsomia

Increased risk of placenta previa

Increased risk of abortion

Increased risk of congenital abnormalities

Increased risk of candidialvulvovaginitis

 

Answer: B* Increased risk of placenta previa

 

***) All of the following are effects of diabetes on pregnancy, except:

Pre-eclampsia

Intrauterine fetal death

Increased incidence of fetal congenital abnormalities

Oligohydramnios

Shoulder dystocia

 

Answer: D* Oligohydramnios

 

***) All of the following are associated with complications in pregnant patient with diabetes mellitus, except:

Maternal ketoacidosis

Intrauterine fetal death

Trichomonas infection

Polyhydramnios

Pre-eclamptic toxemia

 

Answer: C* Trichomonas infection

 

***) Indications of glucose tolerance test during pregnancy include all following, except:

Family history of diabetes

Renal glucosuria

Unexplained stillbirth

Polyhydramnios

Delivery of 4.5 kg baby

 

Answer: B* Renal glucosuria

 

***) In a pregnant patient with history of diabetes in both parents, the probability of abnormal glucose metabolism is:

10%

25%

50%

75%

100%

 

Answer: C*50%

 

***) Which one of the following contributes to good control of diabetes in pregnancy:

300 mg carbohydrate per day diet

Good control of protein intake

Oral hypoglycemic drugs in mild cases

Twice daily mixture of short and medium acting insulin

Bed rest in the last 3 months of pregnancy

 

Answer: D* Twice daily mixture of short and medium acting insulin

 

***) In diabetes with pregnancy, there is an increased incidence of:

Traumatic delivery

Maternal death

Maternal head trauma

Normoglycemia

Delivery at home

 

Answer: A* Traumatic delivery

 

Hypertension.

***) Pre-existing raised blood pressure before pregnancy or in early pregnancy may be due to the following, except:

Pre-eclampsia

Essential hypertension

Renal artery stenosis

Pheochromocytoma

Coarctation of aorta

 

Answer: A* Pre-eclampsia

 

***) Concerning pregnancy induced hypertension, all the following are true except:

Common in women with diabetes mellitus

Treatment includes furosemide (Lasix)

Albuminuria is due to this condition

Delivery usually cure this condition

Will recur in 30% of cases in subsequent pregnancies

 

Answer: B* Treatment includes furosemide (Lasix)

 

***) Concerning gestational hypertension, all the following are true except:

The blood pressure rises all through pregnancy

The blood pressure decreases few days after delivery

The hypertension is not necessarily to be associated with proteinuria

The pregnancy should not exceed more than 40 weeks

The blood pressure rises in the third trimester

 

Answer: A* The blood pressure rises all through pregnancy

 

***) One of the following statements regarding pregnancy induced hypertension is true:

Can be relieved by use of diuretics

Post partum pregnancy induced hypertension is the most dangerous

Relief of pregnancy induced hypertension is achieved by anti-tetanus toxoid

Death of the fetus is usually followed by complete improvement

Fetus is usually large for date

 

Answer: B* Post partum pregnancy induced hypertension is the most dangerous

 

Eclampsiaand Pre-eclampsia.

***) All of the following conditions are more likely to be associated with pre-eclampsia, except:

Multiparity

Multiple pregnancy

Chronic kidney disease

Diabetes mellitus

Vesicular mole

 

Answer: A* Multiparity

 

***) The following conditions are associated with high frequency of pre-eclampsia, except:

Diabetes

Multiple pregnancy

Polyhydramnios

Hydatiform mole

Placenta previa

 

Answer: C* Polyhydramnios

 

***) The following statements regarding ante partum pre-eclampsia toxemia are true, except:

Treatment with diuretics is of great value

Primary treatment with diazoxide is contraindicated

Plasma uric acid level is elevated

Materno-placental blood flow falls to less than 50%

There is increased incidence of PET in future pregnancies

 

Answer: A* Treatment with diuretics is of great value

 

***) The following about a patient developing proteinuric hypertension (pre-eclampsia) in pregnancy are true, except:

Serum uric acid concentration increases

The plasma volume decreases

Placental function tests values decrease

Hb concentration increases

Creatinine clearance increases

 

Answer: E* Creatinine clearance increases

 

***) One of the following is a grave sign of severe pre-eclampsia:

A PCV (Packed cell volume) of 55%

BP 160/100 mm HG

Proteinuria of 2 g/24h

Deep tendon reflex with 3+/4+

Edema of lower limbs up to the knees

 

Answer: D* Deep tendon reflex with 3+/4+

 

***) All the following are symptoms or signs of impending eclampsia, except:

Severe headache

Polyuria

Epigastric pain

Exaggerated reflexes

Visual disturbances

 

Answer: B* Polyuria

 

***) Signs and symptoms of impending eclampsia include all of following, except:

Headache

Sacral edema

Epigastric pain

Hyperreflexia

Blurring of vision

 

Answer: B* Sacral edema

 

***) Signs of fulminating pre-eclampsia include the following, except:

Hyperreflexia

Epigastric tenderness

Poor urine output

Maternal weight loss

Proteinuria

 

Answer: D* Maternal weight loss

 

***) The usual manner of death in case of eclampsia is:

Cerebral hemorrhage

Congestive heart failure

Cardiac arrest during convulsions

Uremia

Hemorrhagic pneumonia

 

Answer: A* Cerebral hemorrhage

 

***) The complications of pre-eclampsia include all of the following, except:

Abruption placenta

Polyhydramnios

Intrauterine growth retardation

Decreased renal blood flow

Abnormal liver enzymes

 

Answer: B* Polyhydramnios

 

***) In a case of pre-eclamptic toxemia at 40 weeks, the best management is:

Induction of labor

Cesarean section

Give methyldopa only

Give diuretics (Lasix) only

Give hydralazine only

 

Answer: A* Induction of labor

 

***) The most worrisome sign or symptom of serious pathology in late pregnancy is:

Swollen ankles

Constipation

Visual changes

Nocturia

Heartburn

 

Answer: C* Visual changes

 

Heart and Pregnancy.

***) Regarding changes in the heart during pregnancy, all the following are true except:

Third sound

Diastolic murmur

Soft systolic murmur

Increased pulse rate

Slight displacement of the apex

 

Answer: B* Diastolic murmur

 

***) Which of the following signs is diagnostic of heart disease in pregnancy:

Diastolic heart murmur

Soft systolic heart murmur

Tachycardia

Arrhythmia

Accentuated first heart sound

 

Answer: A* Diastolic heart murmur

 

***) Which of the following physical signs is least likely to indicate organic heart disease in pregnant woman:

Systolic murmur

Diastolic murmur

Atrial fibrillation

Cardiac enlargement

Palpation of a thrill

 

Answer: A* Systolic murmur

 

***) The following are factors which may lead to heart failure in patient with heart disease in pregnancy, except:

Tachycardia

Emotional upset

Physical exercise

A systolic murmur

Lower limbs edema

 

Answer: D* A systolic murmur

 

***) In a pregnant patient with mitral stenosis, all the following are true except:

To have labor induced at 38 weeks

Sit upright in labor

Could be considered for mitral valvotomy during pregnancy

Should not be given ergometrine (oxytocin) in the third stage of labor

Should have elective forceps delivery unless spontaneous delivery is very rapid

 

Answer: A* To have labor induced at 38 weeks

 

***) Pregnancy is contraindicated in all of the following conditions except:

Uncorrected atrial septal defect

Marfan's syndrome

Uncompensated cardiac failure

Eisenmenger's syndrome

Severe mitral stenosis

 

Answer: A* Uncorrected atrial septal defect

 

Hyperemesis Gravidarum HG.

***) Concerning hyperemesis gravidarum, all the following are true except:

Usually occurs in the first trimester

Is associated with hydatiform mole

Is associated with multiple pregnancy

Occurs most commonly in multigravida

May require admission to the hospital

 

Answer: D* Occurs most commonly in multigravida

 

Jaundice in Pregnancy.

***) The following may cause jaundice during pregnancy, except:

Acute fatty atrophy of the liver

Viral hepatitis

Severe pre-eclampsia

Chlorpromazine

Erythromycin

 

Answer: D* Chlorpromazine