Drugs and Pregnancy OB56-OB57.

 

Drugs and Pregnancy.

***) The following drugs are not given in pregnancy, except:

Tetracycline

Thiazides

Chloramphenicol

Heparin

Warfarin

 

Answer: D* Heparin

 

***) These drugs cross the placenta to the fetus, except:

Heparin

Warfarin

Tetracycline

Diazepam

Aspirin

 

Answer: A* Heparin

 

***) All of the following drugs are teratogenic, except:

Tetracycline

Paracetamol

Thiazides

Stilbestrol

Warfarin

 

Answer: B* Paracetamol

 

***) All of the following drugs are contraindicated in pregnancy, except:

Tetracycline

Iodides

Diphenylhydantoin (Epanutin)

Warfarin

Pyridoxine

 

Answer: E* Pyridoxine

 

***) One of the following drugs can be safe if used during pregnancy:

Warfarin

Septrin

Tetracycline

Erythromycin

Chloramphenicol

 

Answer: D* Erythromycin

 

***) Which of the following drugs given during pregnancy can give "Grey Baby Syndrome":

Ampicillin

Chloramphenicol

Gentamycin

Tetracycline

Streptomycin

 

Answer: B* Chloramphenicol

 

***) Regarding drugs in pregnancy, all the following are true except:

Digitalis does not cross the placenta

Warfarin crosses the placenta

Heparin does not cross the placenta

Hydralazine causes relaxing vascular smooth muscle

Methotrexate crosses the placenta

 

Answer: A* Digitalis does not cross the placenta

 

***) Brown discoloration of the teeth can occur in infants exposed in uterus to:

Penicillin

Tetracycline

Chloramphenicol

Gentamycin

Streptomycin

 

Answer: B* Tetracycline

 

Breastfeeding and Drugs.

***) Milk ejection reflex is affected by one of the following hormones:

Estrogens

Progesterone

Human placental lactogen

Oxytocin

Chorionic gonadotropin

 

Answer: D* Oxytocin

 

***) All of the following drugs are contraindicated during breast feeding except one:

Cytotoxic drugs

Chloramphenicol

Iodine

Heparin

Thiouracil

 

Answer: D* Heparin

 

***) All of the following drugs are contraindicated during breast feeding except one:

Bromocriptine

Cephalosporins

Ergotamine

Cimetidine

Tetracycline

 

Answer: B* Cephalosporins

 

Oxytocin.

***) All of the following are true regarding oxytocin, except:

Prolonged treatment can cause water intoxication

Can cause milk ejection

Single rapid IV injection can cause transient hypotension, tachycardia and ECG changes

It is not effective when given orally

It can cause contraction of the lower uterine segments

 

Answer: E* It can cause contraction of the lower uterine segments

 

***) Regarding oxytocin, one of the following is true:

Induces vigorous sustained uterine contractions

Comes from the anterior pituitary gland

Possesses no antidiuretic activity

Has long half life

Acts on myoepithelial cells of the mammary glands

 

Answer: E* Acts on myoepithelial cells of the mammary glands

 

***) All of the following are complications of Syntocinon (oxytocin) toxicity, except:

Headache

Nausea and vomiting

Polyuria

Coma

Weight gain

 

Answer: C* Polyuria

 

Immunizations.

***) The first immunoglobulin produced in any immune response is:

IgA

IgM

IgD

IgE

IgG

 

Answer: B* IgM

 

***) The only immunoglobulin can cross placenta:

IgM

IgA

IgG

IgE

IgD

 

Answer: C* IgG

 

***) All of the following vaccines are contraindicated during pregnancy, except:

German measles

Tetanus

Mumps

Poliomyelitis

Hepatitis

 

Answer:dddd B* Tetanus

 

***) All of the following vaccines can be given to the pregnant patient after the second trimester, except:

Tetanus toxoid vaccine

Smallpox vaccine

Cholera vaccine

Vaccination against hepatitis B virus

Typhoid vaccine

 

Answer: B* Smallpox vaccine

 

***) Mumps in pregnancy is associated with:

Increase fetal wastage

Lymph reduction defect

Maternal pneumonia

No major complications

Congenital deafness

 

Answer: D* No major complications

 

???) Regarding immunization during pregnancy, which of the following vaccines would be the safest to receive:

Mumps

Poliomyelitis

Rabies

Rubella

HIV

 

Answer: C* Poliomyelitis

 

Drugs.

***) All of the following drugs have effect on the uterine muscle, except:

Salbutamol

Cervidil

Isoxsuprine

Clomiphene citrate

Methergine

 

Answer: D* Clomiphene citrate

 

***) Regarding the actions of hydralazine, all the following are true except:

Increased renal blood flow

Increased cardiac output

Reflex tachycardia

Smooth muscle relaxation

Decreased placental perfusion

 

Answer: E* Decreased placental perfusion

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425) All of the following are complications of post-maturity, except:

Meconium aspiration syndrome

Hypoglycemia

Hypocalcemia

Loss of subcutaneous fat

Hyaline membrane disease

 

Answer: C* Hypocalcemia (It may lead to Hypercalcemia)

 

***) Which of the following is characteristic feature of acute gonococcal urethritis:

Dysuria

Genital ulceration

High fever

Generalized lymphadenopathy

Sweating

 

Answer: 1* Dysuria