Table 1. ANNUALIZED VACCINATION PROTOCOL FOR DOGS AT MODERATE RISK OF EXPOSURE
| Age at vaccination | Vaccine |
| 6–8 weeks | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Optional + Parainfluenza virus |
| 10–12 weeks | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Rabies (1 dose at 12, 14, or 16 weeks of age) Optional + Parainfluenza virus + B. bronchiseptica (killed-parenteral, 2 doses required, 3–4wks apart) + Leptospirosis (serovars as indicated at 12wks or older) |
| 14–16 weeks | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Rabies (now or at 12wks) Optional + Parainfluenza virus + B. bronchiseptica (live-intranasal, 1 dose or the 2nd killed-parenteral dose) + Leptospirosis (serovars as indicated |
| +1 year | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Rabies (booster required) Optional + B. bronchiseptica (intranasal or parenteral) + Parainfluenza + Leptospirosis (serovars as indicated) |
| +2 years | Optional + B. bronchiseptica (intranasal or parenteral) + Leptospirosis (serovars as indicated) |
| +3 years | Optional + B. bronchiseptica (intranasal or parenteral) + Leptospirosis (serovars as indicated) |
| +4 years | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Rabies Optional + B. bronchiseptica (parenteral) + Parainfluenza + Leptospirosis (serovars as indicated) |
| +5 years | Optional + B. bronchiseptica (parenteral) + Leptospirosis (serovars as indicated) |
| +6 years | Optional + B. bronchiseptica (parenteral) + Leptospirosis (serovars as indicated) |
| +7 years | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Rabies Optional + B. bronchiseptica (parenteral) + Parainfluenza + Leptospirosis (serovars as indicated) |
| Beyond 7 years | Cycle repeats as indicated |
Table 2. DEFINING CRITERIA FOR MODERATE-RISK CANINES (APPLIES TO MOST DOGS)
B. Bronchiseptica Vaccination Is Indicated If
Dog is ever boarded in a commercial kennel
Dog requires occasional grooming
Dog regularly has supervised walks/runs outside with likelihood of contact with other dogs
Parainfluenza* Vaccination Is Indicated If
Dog is ever boarded in a commercial kennel
Dog requires occasional grooming
Dog regularly has supervised walks/runs outside with likelihood of contact with other dogs
Leptospira Vaccination Is Indicated If
The dog is 12wks of age or older
Dog has opportunities for unsupervised outdoor activities
Cases of leptospirosis are known to have been confirmed in the area†
Dog has access (supervised or otherwise) to areas inhabited by “reservoir” hosts (e.g., opossum, skunk, raccoon, vole) or other domestic animals such as cattle, pigs, or horses