Lyme Borreliosis Vaccination Is Not Indicated Because
Dog does not reside in a known Lyme borreliosis endemic area
Dog does not travel to known endemic areas
Dog neither lives in or travels into a known tick-vector area
Dog is reliably treated with topical flea and tick preparation
Dog has never known a tick and never will
Table 5. ANNUALIZED VACCINATION PROTOCOL FOR DOGS AT HIGH RISK OF EXPOSURE
| Age at vaccination | Vaccine |
| 6–8 weeks | Recombinant Distemper Parvovirus Adenovirus-2 Parainfluenza B. bronchiseptica (intranasal recommended) |
| 10–12 weeks | Recombinant Distemper Parvovirus Adenovirus-2 Parainfluenza Rabies (at 12, 14, or 16 weeks) B. bronchiseptica (intranasal recommended) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| 14–16 weeks | Recombinant Distemper Parvovirus Adenovirus-2 Parainfluenza B. bronchiseptica (intranasal recommended) Rabies (now or at 12wks) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| +1 year | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Parainfluenza B. bronchiseptica (intranasal or parenteral) Rabies (required) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| +2 years | B. bronchiseptica (intranasal or parenteral) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| +3 years | B. bronchiseptica (intranasal or parenteral) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| +4 years | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Parainfluenza B. bronchiseptica (intranasal or parenteral) Rabies (required) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| +5 years | B. bronchiseptica (intranasal or parenteral) Optional: + Leptospirosis + Lyme borreliosis (recombinant) |
| +6 years | B. bronchiseptica (intranasal or parenteral) Optional: + Leptospirosis + Lyme borreliosis (recombinant) |
| +7 years | Distemper (MLV or recombinant) Parvovirus Adenovirus-2 Parainfluenza B. bronchiseptica (intranasal or parenteral) Rabies (required) Optional + Leptospirosis + Lyme borreliosis (recombinant) |
| Beyond 7 years | Cycle repeats as indicated |
Table 6. DEFINING CRITERIA FOR HIGH-RISK CANINES
B. Bronchiseptica Booster Is Indicated If
Dog is regularly boarded in a commercial kennel
Dog is routinely groomed at a facility where other dogs are maintained
Dog is regularly allowed outdoors and is unsupervised
Dog has regular exposure to other, unknown dogs
Dog is on a first-name basis with animal control officers