III. Post-reading activities. Answer the following questions
Answer the following questions.
1. What can you say about the composition of Septozyl?
2. What is Septozyl effective for?
3. What are the indications of Septozyl?
4. What do you know about the application of this medicine?
5. What are the side effects of Septozyl?
6. In what case is Septozyl contraindicated for women?
7. Is this drug recommended for those who have severe renal diseases?
8. Name some more contraindications of Septozyl.
Translate into English.
1. Для місцевого застосування.
2. Протиалергічна дія.
3. Різноманітні форми дерматитів.
4. Довготривале використання.
5. Вагітність.
6. Кровотеча.
IV. Speaking
Read the quotation and guess its meaning. Do you agree with it? Comment your point of view.
Half of the modern drugs could well be thrown out of the window, except that
the birds might eat them. (M.H. Fisher)
Notes: to throw — викидати; except — крім.
V. Supplement
1. Fill in the first part of the table.
| Trade name | Indica-tions | Dosage | Precautions | Mode of use (Administration) | |
| DIC (diclofenac) | What I know | ||||
| Panadol | |||||
| DIC (diclofenac) | What I have learned | ||||
| Panadol |
2. Fill in the second part of the table after reading the medication summaries.
3. Compare your ideas with your partner's.
Text 1
DIC
(Diclofenac)
Composition
a) Each enteric coated tablet contains Diclofenac Sodium 25 mg.
b) Each enteric coated tablet contains Diclofenac Sodium 50 mg.
c) Each enteric coated tablet contains Diclofenac Sodium 100 mg. DIC INJECTION
d)Each ml of injection contains Diclofenac Sodium 25 mg.
Description
DIC (Diclofenac) is a potent non-steroidal anti-inflammatory drug ( NSAID) with analgesic and antipyretic properties. It also has some uricosuric1 effect. Diclofenac inhibits cyclo-oxygenase activity with a reduction in the tissue production of prostaglandins such as PgF2 and PgE2. The anti-inflammatory effect, measured in the adjuvant induced arthritis model is greater than that of aspirin and similar to indomethacin.
Indications
■ Rheumatoid arthritis.
■ Osteoarthritis.
■ Low back pain and other acute musculoskeletal disorders such as tendonitis2, tenosynovitis, bursitis, sprains3, strains and dislocations.
■ Ankylosing spondylitis4.
■ Acute gout.
■ Control of pain and inflammation in orthopaedic, dental and other minor surgery.
■ Juvenile chronic arthritis.
■ Postoperative pain.
■ Pain of renal colic.
Contraindications
Active or suspected peptic ulcer or gastrointestinal bleeding. Previous sensitivity to diclofenac sodium. Asthmatic patients in whom attacs of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAID's possessing prostaglandin synthetase inhibiting activity.
Dosage and adminstration
A) Oral.
For symptomatic relief of rheumatoid arthritis, the usual daily dosage is 150 to 200 mg given in two to four divided doses.
For osteoarthritis, 100 to 150 mg is given daily in two or three divided doses.
For ankylosing spondylitis, 100 to 125 mg is given daily in four or five divided doses.
B) Parenteral.
75 mg i.m. 1—2 times daily by deep intragluteal injection for 2—3 days.
Precautions
DIC (Diclofenac) may be used cautiously in patients with history of dyspepsia5, or other g.i. disorders, blood coagulation disorders, severe hepatic or renal disease. Perform blood counts during long-term therapy. Safety in pregnancy, lactation and children has not been established.
Presentation
DIC tablets of 25 mg, 50 mg and 100 mg are available in pack of 10's and in bulk pack of 1000's.
DIC injection is available in clear glass ampoules of 3 ml.
Notes:
1uricosuric — засіб, що допомагає виведенню сечової кислоти
2tendonitis — тендиніт (дистрофія тканини сухожилля)
3sprain — розтягнення зв'язок
4spondylitis — спондиліт (запалення всіх або деяких структурних елементів хребта)
5dyspepsia — диспепсія (розлад травлення)